Mercapto-substituted hydroxyethyl-(triazol-l-yl) derivatives

Details Mercapto-substituted hydroxyethyl-(triazol-l-yl) derivatives Mercapto-substituted hydroxyethyl-(triazol-l-yl) derivatives

1987-08-31

1990-02-06

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548262, A01N 43653, C07D24912

Patent

active

048988758

ABSTRACT:
Novel mercapto-substituted hydroxyethyl-(triazol-l-yl) derivatives of the formula ##STR1## in which Ar represents optionally substituted aryl,
X represents oxygen, sulphur, a direct bond or the groupings --CH.sub.2 --, --CH.sub.2 --CH.sub.2 --, --O--CH.sub.2 --, --SCH.sub.2 --, --O--CH.sub.2 --CH.sub.2 --, and --S--CH.sub.2 --CH.sub.2 --, the hetero atom being bonded to the aryl radical if X represents --OCH.sub.2 --, --SCH.sub.2 --, --O--CH.sub.2 --CH.sub.2 -- or --S--CH.sub.2 --CH.sub.2 -- and
R represents hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted cycloalkyl, optionally substituted cycloalkylalkyl, optionally substituted aralkyl or optionally substituted phenyl, and their acid addition salts and metal salt complexes are very effective as fungicides and parasiticides. Novel oxiranes of the formula ##STR2## in which Ar and X have the above-mentioned meaning, and their use as intermediates for the synthesis of the mercapto-substituted hydroxyethyl-(triazol-l-yl) derivatives.

REFERENCES:
patent: 4097599 (1978-06-01), Evans et al.
patent: 4549900 (1985-10-01), Kramer et al.
patent: 4560697 (1985-12-01), Richardson et al.
patent: 4584308 (1986-04-01), Elbe et al.
patent: 4618619 (1986-10-01), Regel et al.
patent: 4717734 (1988-01-01), Rogers et al.
patent: 4734126 (1988-03-01), Holmwood et al.

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