Process for producing L-lysine

Details Process for producing L-lysine Process for producing L-lysine

1989-05-25

1990-09-04

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

435 691, 435116, 4351721, 4351723, 435170, 43525232, 435840, 435843, 435232, 536 27, C12N 121, C12N 988, C12N 1503, C12N 1531

Patent

active

049544411

ABSTRACT:
A process for producing L-lysine is disclosed in which a recombinant vector, a DNA fragment of which contains a gene involved in the synthesis of dihydropicolinic acid synthetase, is used to transform a microorganism of the genus Corynebacterium or Brevibacterium. The transformant is then cultured in a medium which supports the accumulation of L-lysine. Subsequently the L-lysine is recovered from the culture broth.

REFERENCES:
patent: 4495283 (1985-01-01), Araki et al.
patent: 4560654 (1985-12-01), Miwa et al.
patent: 4601983 (1984-06-01), Nakamori et al.
patent: 4861722 (1989-08-01), Sano et al.
Richard et al., CR Seances Acad. Sci., Ser. 3, 1981, 293(9), CA 96, 194398n, 507-512 (1981).
Simms et al, J. Biol. Chem. (1984), vol. 259, #5, pp. 2734-2741.

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