Antipsychotic hexahydro-2H-indeno[1,2-c]pyridine derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514267, 544 54, 544263, 544278, 544281, 544282, 544321, C07D51900, A61K 31505

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active

050753150

ABSTRACT:
Novel hexahydro-2H-indeno[1,2-c]pyridines and their pharmaceutically acceptable acid addition salts having useful antipsychotic properties.

REFERENCES:
patent: 3678057 (1972-07-01), Ebnother et al.
patent: 4957916 (1990-09-01), Kennis
Journal of Medicinal Chemistry--15(5), 466-470 (1972) Relationship between Antihistamine and Antidepressant Activity in Hexahydroindenopyridines.
Mutat. Res., 66(2), 113-127 (1979)--Actions of an Antispermatogenic, but Non-Mutagenic, Indenopyridine Derivative in Mice and Salmonella typhimurium.
J. Med Chem., 23, 949-952 (1980) hexahydrophyrido[4,3-b]indoles useful as neuroleptics.
J. Med. Chem., 29 8-19 (1986) Neuroleptic Activity of Chiral trans-Hexahydro-y-carbolines.

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