Resolution of enantiomers of 2-(phenyl or phenoxy/propionic acid

Details Resolution of enantiomers of 2-(phenyl or phenoxy/propionic acid Resolution of enantiomers of 2-(phenyl or phenoxy/propionic acid

1987-08-05

1988-11-22

Lone, Werren B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

546295, 71 92, 71 94, 71109, 71116, 560 21, 560 45, 560 59, 560 61, 560 56, 560 62, 560100, 560102, 560105, 562401, 562402, 562469, 562472, C07D24136, C07D21172, C07B 5700

Patent

active

047867310

ABSTRACT:
A method for the chromatographic resolution and analysis of the enantiomers of 2-(phenyl or phenoxy)propionic acids or the C.sub.1 -C.sub.4 alkyl esters thereof which comprises converting a racemic or partially resolved mixture of said 2-(phenyl or phenoxy)propionic acids or the C.sub.1 -C.sub.4 alkyl esters thereof to a pair of diastereomeric 2-amino-1-alkanol derivatives by reaction with an optically active 2-amino-1-alkanol, and analyzing the diastereomeric mixture by gas chromatography.

REFERENCES:
patent: 3954442 (1976-05-01), Becker et al.
patent: 4332960 (1982-06-01), Trosken et al.
patent: 4531969 (1985-07-01), Nestler et al.
patent: 4550192 (1985-10-01), Rogers et al.
Souter, Chromatographic Separations of Stereoiomers, CRC Press, Boca Raton, Fla., pp. 68-69, (1985).

Affiliated with

Also associated with

Rating

Resolution of enantiomers of 2-(phenyl or phenoxy/propionic acid does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Resolution of enantiomers of 2-(phenyl or phenoxy/propionic acid, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Resolution of enantiomers of 2-(phenyl or phenoxy/propionic acid will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-436197