Treatment of allograft rejection with mycophenolic acid morpholi

Details Treatment of allograft rejection with mycophenolic acid morpholi Treatment of allograft rejection with mycophenolic acid morpholi

1988-01-22

1988-11-22

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514470, 514885, A61K 31535

Patent

active

047866373

ABSTRACT:
The compounds and pharmaceutical compositions of Formula A, wherein Z is hydrogen or --C(O)R, Y is hydrogen or morpholinoethyl, and where R is lower alkyl or aryl, and the pharmaceutically acceptable salts thereof, are useful as immunosuppressive agents, particularly for treatment of allograft rejection, especially including cardiac allograft rejection, pancreatic allograft rejection and renal allograft rejection, and for treating autoimmune diabetes. ##STR1##

REFERENCES:
patent: 3868454 (1975-02-01), Johnson
"Antitumor Activity of Derivatives of Mycophenolic Acid", Suzuki et al., J. Antibiotics, 29(3), 275-285, 1975.
"A gastroprotective Anti-inflammatory agent: the .beta.-morpholinoethyl ester of niflumic acid (morniflumate)", Schiantarelli, et al., Agents and Actions, 14(2), 1984.

Affiliated with

Also associated with

Rating

Treatment of allograft rejection with mycophenolic acid morpholi does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Treatment of allograft rejection with mycophenolic acid morpholi, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Treatment of allograft rejection with mycophenolic acid morpholi will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-435518