Thiadiazole guanidines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548138, C07D28512, A61K 3141

Patent

active

047866276

ABSTRACT:
Thiadiazole guanidines of formula 1 ##STR1## wherein R is hydrogen or C.sub.1-4 alkyl and their non-toxic salts. Processes for their preparation and pharmaceutical compositions thereof. The compounds exhibit anti-convulsant activity and are indicated for use in the treatment of epilepsy.

REFERENCES:
patent: 4147794 (1979-04-01), Turner
J. Med. Chem, 1987, 30, 951.
J. Med. Chem, 1986, 29, 2273.
J. Med. Chem., 1986, 29, 2280.

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