Controlled release therapeutic system for a liquid pharmaceutica

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

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424493, 424494, 424495, 424498, A61K 916

Patent

active

052962369

ABSTRACT:
Disclosed is a controlled release pharmaceutical dosage form, including: (a) microgranules of a pharmaceutical and an excipient; (b) a plurality of polymeric lipidic and wax-like coatings applied to the microgranules, the coated microgranules having dimensions which allow suspension of the coated microgranules in a liquid administration vehicle; and (c) a liquid administration vehicle for the coated microgranules, the vehicle including an effective amount of the pharmaceutical in a form immediately available upon ingestion. A process for the preparation of the controlled release therapeutic system is also described.

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W. P. O'Neill, Chapter 4, Controlled Release Technologies: Methods, Theory, and Applications, Kydonieus (ed.), CRC Press, Inc., Boca Raton, Florida (1980).

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