Process for preparing 2-isopropenyl oxazoline

Details Process for preparing 2-isopropenyl oxazoline Process for preparing 2-isopropenyl oxazoline

1990-06-22

1991-07-23

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

564137, 564208, C07D26310

Patent

active

050345362

ABSTRACT:
Unsaturated esters with an alkyl group at the 2 carbon, such as methyl methacrylate, react with .beta.-aminoalkanols, such as 2-aminoethanol, in the presence of an alkali metal alkoxide or hydroxide such as sodium methoxide, under moderate temperatures to form an amide such as N-(2-hydroxyethyl)methacrylamide. The amide may be cyclized by a weak Lewis acid, such as ferric chloride, at about 220.degree. C. to form a 2-alkenyl oxazoline, such as isopropenyl oxazoline.

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