Process for producing 2,6-dideoxy-2-fluoro-L-talopyranose

Details Process for producing 2,6-dideoxy-2-fluoro-L-talopyranose Process for producing 2,6-dideoxy-2-fluoro-L-talopyranose

1990-03-06

1991-07-23

Peselev, Elli

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 41, 536 64, C07H 100

Patent

active

050345176

ABSTRACT:
2,6-Dideoxy-2-fluoro-L-talopyranose and 1-substituted derivatives thereof, including methyl 2,6-dideoxy-2-fluoro-L-talopyranoside and 3,4-di-O-protected-2,6-dideoxy-2-fluoro-L-talopyranosyl halides, are now provided and these new compounds are useful as intermediates for use in the synthesis of new compounds having antitumor activity, especially 7-O-(2,6-dideoxy-2-fluoro-.alpha.-L-talopyranosyl) daunomycinone or -adriamycinone. 2,6-Dideoxy-2-fluoro-L-talopyranose shows antibacterial activity. 2,6-Dideoxy-fluoro-L-talopyranose and the 1-substituted derivatives thereof may be produced by a multi-stage process starting from L-fucose.

REFERENCES:
Morrison et al., Organic Chemistry, 3rd ed. (1979), pp. 529, 564 and 636.

Affiliated with

Also associated with

Rating

Process for producing 2,6-dideoxy-2-fluoro-L-talopyranose does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for producing 2,6-dideoxy-2-fluoro-L-talopyranose, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for producing 2,6-dideoxy-2-fluoro-L-talopyranose will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-433407