Method for reducing or maintaining intraocular pressure

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

Other Related Categories

514913, A61K 4376

Type

Patent

Status

active

Patent number

050344064

Description

ABSTRACT:
A method of reducing or maintaining intraocular pressure in a mammalian eye, e.g., affected with glaucoma, is disclosed. This method comprises administering directly to the mammalian eye an effective amount of one or more 2-cycloalkylamino oxazolines, salts thereof, bases thereof and mixtures thereof.

REFERENCES:
patent: 3598833 (1971-08-01), Hiltmann et al.
patent: 3676798 (1972-07-01), Guilk et al.
patent: 4861760 (1989-08-01), Mazuel et al.
Review: A Synopsis of Recent Developments in Antiglaucoma Drugs, Marsha A. McLaughlin and George C. Y. Chiou.
Editorial: Intraocular Pressure and Glaucoma, Alfred Sommer.
German Article: Stereochemische Untersuchungen uber Arzneimittel. 4 Mitt. (*) Konformation and antihypertensive Wirksamkeit von 2-(2,6-Dialkycyclohexyl)-amino-2-oxazolinen (**) Hiltmann, Kurz, Wollweber and Stoepel.

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