Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...
Reexamination Certificate
2011-01-07
2011-12-06
Mui, Christine T (Department: 1774)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
C436S811000, C436S814000
Reexamination Certificate
active
08071283
ABSTRACT:
This invention generally relates to methods, apparatus, and computer program code for antenatal screening for chromosomal abnormalities, in particular Down's Syndrome. A method of determining a likelihood of a fetus carried by a pregnant mother having a chromosomal abnormality, a first biological, parameter being suitable for screening said fetus for said chromosomal abnormality, the method comprising: receiving first data from a first stage of pregnancy of said mother, said first data comprising data representing a first value of said first biological parameter; receiving second data from a second, later stage of said pregnancy, said second data comprising data representing a second value of said first biological parameter; and determining likelihood data from said first and second data, said likelihood data representing the likelihood of said fetus having a chromosomal abnormality.
REFERENCES:
patent: 5906944 (1999-05-01), Davies
patent: 0800085 (1997-10-01), None
patent: 9956132 (1999-11-01), None
Benattar et al., “Efficiency of Ultrasound and Biochemical Markers for Down's Syndrome Risk Screening. A Prospective Study,” Fetal Diagnosis and Therapy, 14:112-117, 1999.
International Search Report and Written Opinion for International Patent Application No. PCT/GB20041003013, mailed from the International Searching Authority on Nov. 8, 2005, 10 pgs.
EPO Communication for EP Application No. 04743354.5 mailed Dec. 12, 2010 regarding observations by a third party concerning the patentability of the invention, 4 pgs.
Wright et al., “Cross-trimester repeated measures testing for Down's syndrome screening: an assessment,” Health Technology Assessment, vol. 14, No. 33, 92 pgs., Jul. 2010.
K&L Gates LLP
Mui Christine T
University of Plymouth
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