Polymorphs of succinate salt of...

Details Polymorphs of succinate salt of... Polymorphs of succinate salt of...

2007-11-29

2011-12-27

Balasubramanian, Venkataraman (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C514S274000

Reexamination Certificate

active

08084605

ABSTRACT:
Compositions comprising the succinate salt of 2-[6-(3-Amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethyl]-4-fluoro-benzonitrile (referred to herein as Compound I) which has the formula:wherein the Compound I is present in one or more polymorphic forms. Also provided are novel methods for the preparation of the polymorphs of Compound I, and kits and articles of manufacture of the compositions, and methods of using the compositions to treat various diseases.

REFERENCES:
patent: 3322756 (1967-05-01), Hilmer et al.
patent: 3544570 (1970-12-01), Timmler et al.
patent: 3823135 (1974-07-01), Pilgram et al.
patent: 3960949 (1976-06-01), Ahrens et al.
patent: 4494978 (1985-01-01), Chan
patent: 4687777 (1987-08-01), Meguro et al.
patent: 4935493 (1990-06-01), Bachovchin et al.
patent: 5002953 (1991-03-01), Hindley
patent: 5366862 (1994-11-01), Venton et al.
patent: 5387512 (1995-02-01), Balani et al.
patent: 5433955 (1995-07-01), Bredehorst et al.
patent: 5462928 (1995-10-01), Bachovchin et al.
patent: 5512549 (1996-04-01), Chen et al.
patent: 5543396 (1996-08-01), Powers et al.
patent: 5580979 (1996-12-01), Bachovchin
patent: 5601986 (1997-02-01), Takacs
patent: 5614379 (1997-03-01), MacKellar
patent: 5614492 (1997-03-01), Habener
patent: 5624894 (1997-04-01), Bodor
patent: 5798344 (1998-08-01), Kuroki et al.
patent: 5811278 (1998-09-01), Okamura et al.
patent: 5811281 (1998-09-01), Quaroni et al.
patent: 5814460 (1998-09-01), Venton et al.
patent: 5885997 (1999-03-01), Lohray et al.
patent: 5939560 (1999-08-01), Jenkins et al.
patent: 5965532 (1999-10-01), Bachovchin
patent: 5985884 (1999-11-01), Lohray et al.
patent: 6006753 (1999-12-01), Efendic
patent: 6011155 (2000-01-01), Villhauer
patent: 6090786 (2000-07-01), Augustyns et al.
patent: 6107317 (2000-08-01), Villhauer
patent: 6110949 (2000-08-01), Villhauer
patent: 6124305 (2000-09-01), Villhauer
patent: 6129911 (2000-10-01), Faris
patent: 6156739 (2000-12-01), Griffin et al.
patent: 6166063 (2000-12-01), Villhauer
patent: 6172081 (2001-01-01), Damon
patent: 6184020 (2001-02-01), Blinkovsky et al.
patent: 6201132 (2001-03-01), Jenkins et al.
patent: 6214340 (2001-04-01), Takeuchi et al.
patent: 6235493 (2001-05-01), Bissell et al.
patent: 6251391 (2001-06-01), Wilkinson et al.
patent: 6258597 (2001-07-01), Bachovchin
patent: 6261794 (2001-07-01), Chang
patent: 6265551 (2001-07-01), Duke-Cohan et al.
patent: 6303661 (2001-10-01), Demuth et al.
patent: 6309868 (2001-10-01), Monod
patent: 6310069 (2001-10-01), Lohray et al.
patent: 6319893 (2001-11-01), Demuth et al.
patent: 6325989 (2001-12-01), Duke-Cohan et al.
patent: 6335429 (2002-01-01), Cai et al.
patent: 6337069 (2002-01-01), Grouzmann et al.
patent: 6342611 (2002-01-01), Weber et al.
patent: 6355614 (2002-03-01), Wallner
patent: 6380398 (2002-04-01), Kanstrup et al.
patent: 6395767 (2002-05-01), Robl et al.
patent: 6432969 (2002-08-01), Villhauer
patent: 6447772 (2002-09-01), Houston
patent: 6448045 (2002-09-01), Levine et al.
patent: 6458924 (2002-10-01), Knudsen et al.
patent: 6485955 (2002-11-01), Huber et al.
patent: 6495544 (2002-12-01), Hansen, Jr. et al.
patent: 6518277 (2003-02-01), Sadhu et al.
patent: 6521644 (2003-02-01), Broqua
patent: 6528486 (2003-03-01), Larsen et al.
patent: 6545170 (2003-04-01), Pitzele et al.
patent: 6548481 (2003-04-01), Demuth et al.
patent: 6548529 (2003-04-01), Robl et al.
patent: 6555519 (2003-04-01), Washburn
patent: 6555521 (2003-04-01), Hermeling et al.
patent: 6559188 (2003-05-01), Gatlin et al.
patent: 6573096 (2003-06-01), Chen
patent: 6573287 (2003-06-01), Sulsky et al.
patent: 6586198 (2003-07-01), Brown
patent: 6608038 (2003-08-01), Caplan et al.
patent: 6617340 (2003-09-01), Villhauer
patent: 6620821 (2003-09-01), Robl
patent: 6620910 (2003-09-01), Calas et al.
patent: 6627636 (2003-09-01), Robl
patent: 6645995 (2003-11-01), Kanstrup et al.
patent: 6664273 (2003-12-01), Burnett et al.
patent: 6673815 (2004-01-01), Devasthale et al.
patent: 6673829 (2004-01-01), Dorwald et al.
patent: 6686337 (2004-02-01), Connor
patent: 6699871 (2004-03-01), Edmondson et al.
patent: 6703238 (2004-03-01), Bachovchin
patent: 6706742 (2004-03-01), De Nanteuil et al.
patent: 6710040 (2004-03-01), Hulin et al.
patent: 6716843 (2004-04-01), De Nanteuil et al.
patent: 6727261 (2004-04-01), Gobbi et al.
patent: 6727271 (2004-04-01), Cheng et al.
patent: 6747035 (2004-06-01), Guadilliere et al.
patent: 6800650 (2004-10-01), Boehringer et al.
patent: 6803357 (2004-10-01), Bachovchin et al.
patent: 6825169 (2004-11-01), Bachovchin et al.
patent: 6861440 (2005-03-01), Boehringer et al.
patent: 6867205 (2005-03-01), Boehringer et al.
patent: 6998502 (2006-02-01), Majeed et al.
patent: 7230000 (2007-06-01), Finer et al.
patent: 7304086 (2007-12-01), Schilling et al.
patent: 7371871 (2008-05-01), Schilling et al.
patent: 7470700 (2008-12-01), Feng et al.
patent: 7781584 (2010-08-01), Feng et al.
patent: 7795428 (2010-09-01), Feng et al.
patent: 2001/0018210 (2001-08-01), Bachovchin et al.
patent: 2001/0020006 (2001-09-01), Demuth et al.
patent: 2001/0031780 (2001-10-01), Kanstrup et al.
patent: 2001/0047078 (2001-11-01), Chang
patent: 2001/0051646 (2001-12-01), Demuth et al.
patent: 2002/0006899 (2002-01-01), Pospisilik et al.
patent: 2002/0016100 (2002-02-01), Okabe et al.
patent: 2002/0019411 (2002-02-01), Robl et al.
patent: 2002/0037829 (2002-03-01), Aronson et al.
patent: 2002/0041871 (2002-04-01), Brudnak
patent: 2002/0049153 (2002-04-01), Bridon et al.
patent: 2002/0049164 (2002-04-01), Demuth et al.
patent: 2002/0061839 (2002-05-01), Scharpe et al.
patent: 2002/0071838 (2002-06-01), Demuth et al.
patent: 2002/0077340 (2002-06-01), Sulsky et al.
patent: 2002/0082292 (2002-06-01), Sahoo et al.
patent: 2002/0082427 (2002-06-01), Demuth et al.
patent: 2002/0103242 (2002-08-01), Sahoo et al.
patent: 2002/0103384 (2002-08-01), Kanstrup et al.
patent: 2002/0110560 (2002-08-01), Demuth et al.
patent: 2002/0115843 (2002-08-01), Oi et al.
patent: 2002/0132979 (2002-09-01), Chen
patent: 2002/0147130 (2002-10-01), Huber et al.
patent: 2002/0147157 (2002-10-01), Connor
patent: 2002/0155565 (2002-10-01), Garin-Chesa et al.
patent: 2002/0164759 (2002-11-01), Travis et al.
patent: 2002/0165164 (2002-11-01), Demuth et al.
patent: 2002/0169159 (2002-11-01), Medina et al.
patent: 2002/0183367 (2002-12-01), Sulsky et al.
patent: 2002/0193390 (2002-12-01), Villhauer
patent: 2002/0198205 (2002-12-01), Himmelsbach et al.
patent: 2002/0198242 (2002-12-01), Demuth et al.
patent: 2002/0198380 (2002-12-01), Belzer et al.
patent: 2003/0008905 (2003-01-01), Demuth et al.
patent: 2003/0008925 (2003-01-01), Esteve et al.
patent: 2003/0027282 (2003-02-01), Huber et al.
patent: 2003/0040478 (2003-02-01), Drucker et al.
patent: 2003/0045464 (2003-03-01), Hermeling et al.
patent: 2003/0055052 (2003-03-01), Peters et al.
patent: 2003/0060412 (2003-03-01), Prouty et al.
patent: 2003/0060434 (2003-03-01), Nielsen et al.
patent: 2003/0069234 (2003-04-01), Medina et al.
patent: 2003/0087935 (2003-05-01), Cheng et al.
patent: 2003/0087950 (2003-05-01), DeNanteuil et al.
patent: 2003/0089935 (2003-05-01), Fan et al.
patent: 2003/0092630 (2003-05-01), Demuth et al.
patent: 2003/0092697 (2003-05-01), Cheng et al.
patent: 2003/0096846 (2003-05-01), Cheng et al.
patent: 2003/0096857 (2003-05-01), Evans
patent: 2003/0100563 (2003-05-01), Edmondson et al.
patent: 2003/0103968 (2003-06-01), Amelsberg et al.
patent: 2003/0105077 (2003-06-01), Kanstrup et al.
patent: 2003/0119736 (2003-06-01), Demuth et al.
patent: 2003/0119738 (2003-06-01), Niestroj et al.
patent: 2003/0119750 (2003-06-01), Demuth et al.
patent: 2003/0125304 (2003-07-01), Demuth et al.
patent: 2003/0130199 (2003-07-01), von Hoersten et al.
patent: 2003/0130281 (2003-07-01), Boehringer et al.
patent: 2003/0130306 (2003-07-01), Devasthale et al.
patent: 2003/0134802 (2003-07-01), Demuth et al.
patent: 2003/0135023 (2003-07-01), Demuth et al.
patent: 2003/0139429 (2003-07-01), Cohen
patent: 2003/0139434 (2003-07-01), Balkan et al.
patent: 2003/0144206 (2003-07-01), Knudsen et al.
patent: 2003/0148961 (2003-0

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