Theophylline and theobromine derivatives

Details Theophylline and theobromine derivatives Theophylline and theobromine derivatives

1983-04-11

1986-01-14

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514263, 514252, 514253, 544267, 544268, 544269, C07D47308, A61K 3152

Patent

active

045646171

ABSTRACT:
A novel compound has the following formula: ##STR1## in which R.sub.1 and R.sub.2 are methyl or a group having the formula: ##STR2## provided that one of R.sub.1 and R.sub.2 is methyl and the other is said group, wherein R stands for a hydrogen atom or a lower alkyl group, Z stands for a group ##STR3## in which X.sub.1 and X.sub.2, which may be the same or different, stand for a hydrogen atom, a lower alkyl group, a lower alkoxy group, a trifluoromethyl group or a halogen atom, or a pyridyl group or a group ##STR4## in which Y.sub.1 and Y.sub.2, which may be the same or different stand for a hydrogen atom, a lower alkyl group, a lower alkoxy group, a trifluoromethyl group or a halogen atom, X stands for a nitrogen or carbon atom, and n is an integer of from 2 to 10, provided that when R.sub.2 is the group having the formula II, X is not carbon and Z is not pyridyl.

REFERENCES:
patent: 4400381 (1983-08-01), Favier et al.
patent: 4426383 (1984-01-01), Sugimoto et al.

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