Substituted 5H-pyrimido[5,4-b]indoles

Details Substituted 5H-pyrimido[5,4-b]indoles Substituted 5H-pyrimido[5,4-b]indoles

1983-12-16

1986-01-14

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

514235, 514237, 514267, 544115, 544244, 544250, A61K 31505, C07D48704

Patent

active

045646104

ABSTRACT:
Substituted 5H-pyrimido[5,4-b]indoles of Formula I ##STR1## wherein R.sup.2 is halogen; the oxadiazolyl group ##STR2## wherein R" is lower alkyl with up to 3 carbon atoms; C.sub.1-5 -alkyl, cycloalkyl, aralkyl, or aryl; OR.sup.I, SO.sub.n R.sup.I with n being 0, 1, or 2, or ##STR3## wherein R.sup.I is hydrogen, C.sub.1-5 -alkyl, cycloalkyl, aralkyl, or aryl; ##STR4## wherein R.sup.II and R.sup.III are hydrogen, C.sub.1-5 -alkyl, C.sub.3-5 -alkenyl, cycloalkyl, aralkyl, aryl, or, with the connecting N-atom, a 5- or 6-membered heterocyclic ring; and

REFERENCES:
patent: 3635975 (1972-01-01), Kim et al.
Sundberg, et al., J. Org. Chem., vol. 38, No. 19, pp. 3324-3330 (1973).
Senda, et al., Chemical Abstracts, vol. 83, 9964p (1975).
Sedova, et al., Chemical Abstracts, vol. 91, 175296g (1979).
Velezheva, et al., Chemical Abstracts, vol. 93, 204,584y (1980).
Dubovenko, et al., Chemical Abstracts, vol. 94, 121446z (1981).
Suvorov, et al., Chemical Abstracts, vol. 96, 85492s (1982).
Unangst, Chemical Abstracts, vol. 99, 212484e (1983).

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