Substituted arylimidazolone and triazolone as inhibitors of...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S385000, C548S262200, C548S300100

Reexamination Certificate

active

08084481

ABSTRACT:
The present application relates to novel, substituted 4-arylimidazol-2-ones and 5-aryl-1,2,4-triazolones, processes for the production thereof, the use thereof alone or in combinations for the treatment and/or prevention of diseases and the use thereof for the production of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.

REFERENCES:
patent: 5276049 (1994-01-01), Himmelsbach et al.
patent: 5468448 (1995-11-01), Wahi et al.
patent: 5585394 (1996-12-01), Di Malta et al.
patent: 5681841 (1997-10-01), Himmelsbach et al.
patent: 6531142 (2003-03-01), Rabe et al.
patent: 6746989 (2004-06-01), Muller et al.
patent: 6762152 (2004-07-01), Muller et al.
patent: 6838415 (2005-01-01), Muller et al.
patent: 2002/0045651 (2002-04-01), Brenner et al.
patent: 2002/0172644 (2002-11-01), Haslwanter et al.
patent: 2003/0161790 (2003-08-01), Wahi et al.
patent: 2004/0071757 (2004-04-01), Rolf et al.
patent: 2006/0148779 (2006-07-01), Bell et al.
patent: 2008/0095863 (2008-04-01), Kabra et al.
patent: 2010/0261771 (2010-10-01), Bruggemeier et al.
patent: 2327784 (2008-03-01), None
patent: 051829 (1982-05-01), None
patent: 0412594 (1990-07-01), None
patent: 0533276 (1993-03-01), None
patent: 9931099 (1999-06-01), None
patent: 0100595 (2001-01-01), None
patent: WO-02/066447 (2002-08-01), None
patent: WO-2005/006892 (2005-01-01), None
patent: WO-2005/007112 (2005-01-01), None
patent: WO-2005/086836 (2005-09-01), None
patent: WO 2005/105779 (2005-11-01), None
patent: 2006066133 (2006-06-01), None
patent: 2006117657 (2006-11-01), None
R. W. Schrier, M.D. et al., “Hormones and Hemodynamics in Hear Failure,” New England Journal of Medicine, vol. 341, No. 8, (1999), pp. 577-585.
L. De Luca, M.D. et al., “Hyponatremia in Patients with Heart Failure,” American Journal of Cardiology 2005; 96 Supp., 19L-23L.
G. S. Francis, M.D. et al, “Comparison of Neuroendocrine Activation in Patients with Left Ventricular Dysfunction with and without Congestive Heart Failure,” Circulation, 1990; pp. 1724-1929.
P. Sanghi et al., “Vasopressin Antagonism: a Future Treatment Option in Heart Failure,” The European Society of Cardiology, 2005, pp. 538-543.
J. J. Bronson et al., “Discovery of the first Antibacterial Small Molecule Inhibitors of MurB,” Bioorganic & Medicinal Chemistry Letters 13, 2003, pp. 873-875.
Lemmens-Gruber, et al.: Vasopressin antagonists, Cell. Mol. Life Sci. 63 (2006) 1766-1779.
Tang et al.,: Vasopressin receptor antagonists in the management of acute heart failure, Expert Opin. Investig. Drugs, 2005, 14:5, pp. 593-600.
Palm et al., Vasopressin Antagonists as Aquaretic Agents for the Treatment of Hyponatremia, Am. J. Med. (2006) vol. 119 (7A) S87-S92.
U.S. Appl. No. 13/132,897, filed Jun. 15, 2009.
U.S. Appl. No. 12/727,044, filed Feb. 16, 2011.
Francis et al., “Comparison of Neuroendocrine Activation in Patients with Left Ventricular Dysfunction with and without Congestive Heart Failure,” Circulation 1990, vol. 82, 1724-1729.
English translation of WO 2001/00595, filed as U.S. Appl. No. 10/019,247 on Dec. 18, 2001.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Substituted arylimidazolone and triazolone as inhibitors of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted arylimidazolone and triazolone as inhibitors of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted arylimidazolone and triazolone as inhibitors of... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4302242

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.