In vivo and ex vivo gene transfer into renal tissue using...

Details In vivo and ex vivo gene transfer into renal tissue using... In vivo and ex vivo gene transfer into renal tissue using...

2010-05-12

2011-11-01

Schnizer, Richard (Department: 1635)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

C536S023200, C536S023500

Reexamination Certificate

active

08048410

ABSTRACT:
A method for treating a renal disease in a subject is disclosed. The method includes administering into a kidney of the subject with an effective amount of a gutless adenoviral vector containing a polynucleotide encoding a therapeutic agent. The gutless adenoviral vector contains the nucleotide sequence of SEQ ID NO:13 or SEQ ID NO:15 and expresses the therapeutic agent in a kidney tissue of the subject.

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