Artificial lymphoid tissue equivalent

Details Artificial lymphoid tissue equivalent Artificial lymphoid tissue equivalent

2006-06-21

2011-10-04

Wehbe, Anne Marie S (Department: 1633)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Two or more cell types, per se, in co-culture

C435S373000, C435S395000

Reexamination Certificate

active

08030070

ABSTRACT:
The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the normal tissues that interact with vaccines in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interactions with the immune system.

REFERENCES:
patent: 5008116 (1991-04-01), Cahn
patent: 5160490 (1992-11-01), Naughton et al.
patent: 5354686 (1994-10-01), Haberman
patent: 5562910 (1996-10-01), Daynes et al.
patent: 5725856 (1998-03-01), Hudziak et al.
patent: 5739001 (1998-04-01), Brown et al.
patent: 5750329 (1998-05-01), Quinn et al.
patent: 6177282 (2001-01-01), McIntyre
patent: 6274378 (2001-08-01), Steinman et al.
patent: 6479064 (2002-11-01), Atala
patent: 6541225 (2003-04-01), Li
patent: 6835550 (2004-12-01), Estell et al.
patent: 2002/0155108 (2002-10-01), Barbera-Guillem et al.
patent: 2003/0109042 (2003-06-01), Wu et al.
patent: 2003/0147923 (2003-08-01), Klaviniskis
patent: 2003/0199006 (2003-10-01), Britz et al.
patent: 2003/0207287 (2003-11-01), Short
patent: 2004/0009943 (2004-01-01), Semple et al.
patent: 2004/0109876 (2004-06-01), Yamamoto et al.
patent: 2004/0234510 (2004-11-01), Mochitate
patent: 2005/0191743 (2005-09-01), Wu et al.
patent: 2005/0229264 (2005-10-01), Chang et al.
patent: 2005/0282148 (2005-12-01), Warren et al.
patent: 2006/0078540 (2006-04-01), Warren et al.
patent: 2006/0105454 (2006-05-01), Son et al.
patent: 2006/0270029 (2006-11-01), Warren et al.
patent: 2006/0275270 (2006-12-01), Warren et al.
patent: 2007/0015136 (2007-01-01), Sanchez-Schmitz et al.
patent: 2007/0141552 (2007-06-01), Warren et al.
patent: 2007/0154956 (2007-07-01), Warren et al.
patent: 2007/0178076 (2007-08-01), Drake et al.
patent: 2007/0218054 (2007-09-01), Sukumar et al.
patent: 2008/0008653 (2008-01-01), Tew et al.
patent: 2009/0011455 (2009-01-01), Warren et al.
patent: 2009/0104221 (2009-04-01), El Shikh et al.
patent: 2009/0117581 (2009-05-01), Warren et al.
patent: 0 358 506 (1989-09-01), None
patent: 1013668 (2000-06-01), None
patent: 1 437 147 (2002-09-01), None
patent: 1970444 (2006-12-01), None
patent: 99/12972 (1999-03-01), None
patent: WO 99/15629 (1999-04-01), None
patent: WO 99/43788 (1999-09-01), None
patent: WO99/49319 (1999-09-01), None
patent: WO 03/041568 (2003-05-01), None
patent: WO 03/050271 (2003-06-01), None
patent: WO 2004/031361 (2004-04-01), None
patent: WO2004/101773 (2004-11-01), None
patent: 2005/013896 (2005-02-01), None
patent: 2005/072088 (2005-08-01), None
patent: WO 2005/104755 (2005-11-01), None
patent: WO 2007/075979 (2007-07-01), None
patent: 2007/108835 (2007-09-01), None
patent: WO 2007/106559 (2007-09-01), None
patent: WO 2007/146267 (2007-12-01), None
Sarradell et al. (2003) Vet. Pathol., vol. 40, 395-404.
Tan et al. (2005) J. Leuk. Biol., vol. 78, 319-324.
Takeuchi et al. (2004) Clin. Canc. Res., vol. 10, 2351-2358.
Katakai et al. (2004) J. Exp. Med., vol. 200(6), 783-795.
Gunzer et al. (2000) Immunity, vol. 13, 323-332.
John G. Tew et al., “Follicular Dendritic Cells and Presentation of Antigen and Costimulatory Signals to B Cells,” Immunological Reviews (1997), vol. 156, pp. 39-52.
Akiko Furuyama et al., “Assembly of Basement Membrane in vitro by Cooperation Between Alveolar Epithelial Cells and Pulmonary Fibroblasts,” Cell Structure and Function (1997), vol. 22, pp. 603-614.
Stephen F. Badylak et al., “Small Intestinal Submucosa: A Substrate for in vitro Cell Growth,” J. Biomater. Sci. Polymer Edn. (1998), vol. 9, No. 8, pp. 863-878.
Shaoli Zhang et al., “Growth Factors Secreted by Bronchial Epithelial Cells Control Myofibroblast Proliferation: An in vitro Co-culture Model of Airway Remodeling in Asthma,” Laboratory Investigation (1999), vol. 79, No. 4, pp. 395-405.
H. Garrett Thompson et al., “A Three-dimensional in vitro Model of Angiogenesis in the Airway Mucosa,” Pulmonary Pharmacology & Therapeutics (2007), vol. 20, pp. 141-148.
M. Nakamura et al., “Expression of Leptin in Two-layered Culture of Gastric Mucous Cells and Fibroblasts: Effect of Helicobacter pylori Attachment,” Aliment Pharmacol Ther. (2004), vol. 20, suppl. 1, pp. 125-130.
Martin N. Nakatsu et al., “Angiogenic Sprouting and Capillary Lumen Formation Modeled by Human Umbilical Vein Endothelial Cells(HUVEC)in Fibrin Gels: The Role of Fibroblasts and Angiopoietin-1,” Microvascular Research (2003), vol. 66, pp. 102-112.
Per Brandtzaeg et al., “Mucosal B Cells: Phenotypic Characteristics, Transcriptional, Regulation, and Homing Properties,” Immunological Reviews (2005), vol. 206, pp. 32-63.
Tarte et al., Leukemia, vol. 14, 2000, abstract p. 2182.
Kim et al., “Three-Dimensional Tissue Culture Models in Cancer Biology,” Seminars in Cancer Biology, (2005), 15(5), pp. 365-377.
A. R. Neves, et al., “Dendritic Cells Derived From Metastatic Cancer Vaccinated With Allogeneic Dendritic Cell-Autologous Tumor Cell Hybrids Express More CD86 and Induce Higher Levels of Interferon-Gamma in Mixed Lymphocyte Reactions,” Cancer Immunology and Immunotherapy, (2005), 54(1), pp. 61-66.
S. Büchele et al., “Presentation of Tetanus Toxoid to Autologous T Cells by Dendritic Cells Generated From Human Blood. Improved Specificity With Dendritic Cells Generated Without Fetal Calf Serum,” Advances in Experimental Medicine and Biology, (1997), vol. 417, pp. 233-237.
Bai et al., “Generation of Dendritic Cells From Human Bone Marrow Mononuclear Cells: Advantages From Clinical Applications in Comparison to Peripheral Blood Monocyte Derived Cells,” International Journal of Oncology, (2002), 20(2), pp. 247-253.
K. V. Bromelow et al., “Whole Blood Assay for Assessment of the Mixed Lymphocyte Reaction,” Journal of Immunological Methods, (2001), 247(1-2), pp. 1-8.
M. H. Kosco et al., “Follicular Dendritic Cells and Germinal Center Formation In-Vitro,” Accessory Cells in HIV and Other Retroviral Infections: Morphological and Functional Aspects; Workshop on Morphological and Functional Aspects of Accessory Cells in Tretroviral Infections, Hamberg, Germany, 23-24, p. 44-49 (1991).
M. H. Kosco et al., “Folicular Dendritic Cell-Dependent B-Cell Proliferation and in Vitro Germinal Center,” Lymphatic Tissues In Vivo Immune Responses, (1991), pp. 687-690.
O. Soderberg et al., “The Human Follicular Dendritic Cell Line FDC-1 Binds Immune Complexes and Promotes Somatic Hypermutation,” Blood, (2001), 98(11 part 2), pp. 40b.
R. Tsunoda et al., “Human Follicular Dendritic Cells In Vitro and Follicular Dendritic-Cell-Like Cells,” Cell and Tissue Research, (1997), 288(2), pp. 381-389.
R. Tsunoda et al., “Follicular Dendritic Cells In Vitro Modulate the Expression of Fas and Bcl-2 on Germinal Center B Cells,” Cell and Tissue Research, (2000), 299(3), pp. 395-402.
J. G. Tew et al., “Follicular Dendritic Cells As Accessory Cells,” Immunological Reviews, (1990), No. 117, pp. 185-211.
M. H. Kosco et al., “Follicular Dendritic Cell-Dependent Adhesion and Proliferation of B Cells In Vitro,” Journal of Immunology, (1992), 148(8), pp. 2331-2339.
Y. Wu et al., “Influence of Follicular Dendritic Cells and Primed T Cells on Somatic Hypermutation in In Vitro Germinal Centers,” Journal of Immunology, (2006), 176(suppl. S), pp. S235-S236.
M. El Shikh et al., “Follicular Dendritic Cells Stimulated by Collagen Type I Develop Dendrites and Networks In Vitro,” Cell and Tissue Research, (2007), 329(1), pp. 81-89.
R. Seguin et al., “Human Brain Endothelial Cells Supply Support for Monocyte Immunoregulartory Functions,” Journal of Neuroimmunology, (2003), 135(1-2), pp. 96-106.
S Levenberg et al., “Advances in Tissue Engineering,” Current Topics in Developmental

Affiliated with

Also associated with

Rating

Artificial lymphoid tissue equivalent does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Artificial lymphoid tissue equivalent, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Artificial lymphoid tissue equivalent will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4297505