GDEP enhancer element and use thereof to confer retinal...

Details GDEP enhancer element and use thereof to confer retinal... GDEP enhancer element and use thereof to confer retinal...

2008-12-29

2011-12-27

Singh, Anoop (Department: 1632)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C536S023500, C536S024100, C435S235100, C435S320100, C435S325000

Reexamination Certificate

active

08084229

ABSTRACT:
The present invention is directed to isolated nucleic acids containing functional polynucleotide sequences representing an enhancer element for the Gene Differentially Expressed in Prostate (GDEP). Such molecules are useful in conferring retinal specific transcriptional responsiveness on associated promoters and methods for directing retinal specific gene expression are accordingly disclosed.

REFERENCES:
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Cross et al Med. Oncol. , 2008, 25, 40-49.
Cross DS, et al. Functional characterization of the GDEP promoter and three enhancer elements in retinoblastoma and prostate cell lines. Med Oncol. 2008;25:40-49. Epub Jun. 27, 2007.

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