Chemical apparatus and process disinfecting – deodorizing – preser – Chemical reactor – For radioactive reactant or product
Reexamination Certificate
2008-04-14
2011-12-06
Griffin, Walter (Department: 1774)
Chemical apparatus and process disinfecting, deodorizing, preser
Chemical reactor
For radioactive reactant or product
C422S129000, C422S130000, C422S500000, C422S501000, C422S502000, C422S504000, C422S505000, C422S507000, C422S509000, C422S521000, C422S522000, C422S523000, C422S524000, C422S537000, C422S547000, C422S600000, C422S603000
Reexamination Certificate
active
08071035
ABSTRACT:
Methods and devices for a fully automated synthesis of radioactive compounds for imaging, such as by positron emission tomography (PET), in a fast, efficient and compact manner are disclosed. In particular, the various embodiments of the present invention provide an automated, stand-alone, hands-free operation of the entire radiosynthesis cycle on a microfluidic device with unrestricted gas flow through the reactor, starting with target water and yielding purified PET radiotracer within a period of time shorter than conventional chemistry systems. Accordingly, one aspect of the present invention is related to a microfluidic chip for radiosynthesis of a radiolabeled compound, comprising a reaction chamber, one or more flow channels connected to the reaction chamber, one or more vents connected to said reaction chamber, and one or more integrated valves to effect flow control in and out of said reaction chamber.
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Ball Carroll Edward
Diener Lawrence Talcott
Elizarov Arkadij M
Ford Sean
Kolb Hartmuth C.
Griffin Walter
Ryan Joshua B.
Siemens Medical Solutions USA , Inc.
Young Natasha
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