Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-05-25
2011-11-22
Landau, Sharmila G. (Department: 1611)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
Reexamination Certificate
active
08063083
ABSTRACT:
The present invention relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for treating non-Hodgkin's lymphoma, in a subject in need thereof.
REFERENCES:
patent: 6080772 (2000-06-01), Tang et al.
patent: 6858598 (2005-02-01), McKearn et al.
patent: 7247734 (2007-07-01), Drysdale et al.
patent: 7825148 (2010-11-01), Ying et al.
patent: 2005/0267185 (2005-12-01), Marino et al.
patent: 2006/0167070 (2006-07-01), Ying et al.
patent: 2007/0066831 (2007-03-01), MacDonald et al.
patent: 2007/0155809 (2007-07-01), Ying et al.
patent: 2011/0009397 (2011-01-01), Ying
patent: 2011/0105749 (2011-05-01), Ying
patent: WO 2005/000300 (2005-01-01), None
patent: WO 2006/047631 (2006-05-01), None
patent: WO 2006/055760 (2006-05-01), None
patent: WO 2007/139951 (2007-12-01), None
patent: WO 2007/139960 (2007-12-01), None
patent: WO 2008/021364 (2008-02-01), None
Mitisades et al. HSP90 molecular chaperone a novel therapeutic target for B-cell lymphomas and multiple myeloma. Annals of Oncology. 2002; 13 (Suppl 2): 168, abstract # 601.
Lee et al. Late relapse in patients with diffuse large-cell lymphoma treated with MACOP-B. J Clin Oncol. 1997;15(5):1745-1753; abstract only.
Dias, S. et al., “VEGF165Promotes Survival of Leukemic Cells by Hsp9O-Mediated Induction of Bcl-2 Expression and Apoptosis Inhibition,”Blood, 99(7):2532-2540 (2002).
Valbuena, J.R. et al., “Expression of Heat-Shock Protein-90 in Non-Hodgkin's Lymphomas,”Modern Pathology, 18:1343-1349 (2005).
Rostom, S. A.F., et al., “Polysubstituted Pyrazoles, Part 5.1Synthesis of New 1-(4-chlorophenyl)-4-hydroxy-1H-pyrazole-3-carboxylic acid hydrazide analogs and some derived ring systems. A Novel Class of Potential Antitumor and Anti-HCV Agents,”European Journal of Medicinal Chemistry, vol. 38, pp. 959-974 (2003).
Davis Steven G.
Klinkel Kortney L
Landau Sharmila G.
McCarter & English LLP
Synta Pharmaceuticals Corp.
LandOfFree
Method for treating non-Hodgkin's lymphoma does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for treating non-Hodgkin's lymphoma, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for treating non-Hodgkin's lymphoma will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4293074