Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds antigen or epitope whose amino acid sequence is...
Reexamination Certificate
2009-07-09
2011-11-22
Belyavskyi, Michail (Department: 1644)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Binds antigen or epitope whose amino acid sequence is...
C424S184100
Reexamination Certificate
active
08062637
ABSTRACT:
The present invention relates generally to a method for the treatment and prophylaxis of inflammatory conditions. The present invention is predicated in part on the identification of cells of the monocyte/macrophage lineage being critical for inflammation and, in particular, chronic inflammation. In accordance with the present invention, it is proposed that the reduction in levels of monocyte/macrophage-type cells and/or a reduction in the production of inflammatory and pro-inflammatory mediators by these cells, especially locally, is effective in reducing inflammatory conditions. The present invention further provides animal models useful for screening for reducing levels of monocyte/macrophage-type cells and/or reducing the production of inflammatory and pro-inflammatory mediators of these cells.
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Nagata M, Yamamoto H, Tabe K, Sakamoto Y, Matuo H: Eosinophil-Adhension-Inducing Activity Produced by Antigen-Stimulated Mononuclear Cells Involves GM-C
Campbell Ian Keith
Hamilton John
Belyavskyi Michail
MorphoSys AG
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