Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-09-19
2011-10-18
Wilson, James O (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S253060, C514S299000, C540S575000, C544S363000, C546S112000
Reexamination Certificate
active
08039462
ABSTRACT:
The present invention provides methods and compositions comprising compounds useful for stimulating neurogenesis. The methods and compositions comprising compounds are also useful for inhibiting neuronal degeneration. Thus, the present invention can be used in the treatment of diseases and conditions characterized by neuronal loss and reduced neurogenesis including Alzheimer's disease, stroke, traumatic brain injury, and depression. This invention could also be used for research products including single agents or mixtures of agents to promote, proliferate, differentiate, or maintain neurons from stem or progenitor cells.
REFERENCES:
patent: 3773919 (1973-11-01), Boswell et al.
patent: 4089809 (1978-05-01), Farrior, Jr.
patent: 4233871 (1980-11-01), Alessi
patent: 4438052 (1984-03-01), Weder et al.
patent: 4438253 (1984-03-01), Casey et al.
patent: 4485054 (1984-11-01), Mezei et al.
patent: 4532089 (1985-07-01), MacDonald
patent: 4540786 (1985-09-01), Wright
patent: 4652441 (1987-03-01), Okada et al.
patent: 4686228 (1987-08-01), Campbell et al.
patent: 4897269 (1990-01-01), Mezei
patent: 5100669 (1992-03-01), Hyon et al.
patent: 5665428 (1997-09-01), Cha et al.
patent: 5770222 (1998-06-01), Unger et al.
patent: 5820880 (1998-10-01), Alving et al.
patent: 5888533 (1999-03-01), Dunn
patent: 6287588 (2001-09-01), Shih et al.
patent: 6747002 (2004-06-01), Cheung et al.
patent: 6974818 (2005-12-01), Kyle et al.
patent: 2004/0006091 (2004-01-01), Kyle et al.
patent: 2004/0072818 (2004-04-01), Dunning et al.
patent: WO-0216360 (2002-02-01), None
PCT International Search Report for Application No. PCT/US06/36463 dated Oct. 16, 2007.
EP 06803851 Supplementary European Search Report (search completed Jun. 21, 2010) (2 pages).
Griswold, et al. “Effects of MLN518, a dual FLT3 and KIT inhibitor, on normal and malignant hematopoiesis.” Blood, 104(9):2912-2918 (Nov. 1, 2004) (7 pages).
Kanai et al. “Involvement of an increased spinal TRPV1 sensitization through its up-regulation in mechanical allodynia of CCI rats.” Neuropharmacology, 49:977-984 (2005) (8 pages).
Swanson et al. “Identification and biological evaluation of 4-(3-Trifluoromethylpyridin-2-yl) piperazine-1-carboxylic acid (5-Trifluoromethylpyridin-2-yl) amide, a high affinity TRPV1 (VR1) vanilloid.” J. Med. Chem., 48:1857-1872 (2005) (16 pages).
Srivastava, et al. “Thiophene-fused quinoline analogues: Facile synthesis of 3-amino-2-cyanothieno [2, 3-b] quinolines from 2-chloro-3-cyanoquinolines.” Indian Journal of Chemistry, 44B:2077-2081 (Oct. 2005) (5 pages).
Neuronascent, Inc.
Sackey Ebenezer O
Wilmer Cutler Pickering Hale and Dorr LLP
Wilson James O
LandOfFree
Methods and compositons for stimulating neurogenesis and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods and compositons for stimulating neurogenesis and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and compositons for stimulating neurogenesis and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4285327