Preparation of isoxazolin-3-ylacylbenzenes

Details Preparation of isoxazolin-3-ylacylbenzenes Preparation of isoxazolin-3-ylacylbenzenes

2011-03-02

2011-11-01

Stockton, Laura L. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

08049017

ABSTRACT:
A process is described for preparing isoxazoles of the formula Iwhere the substituents are as defined below:R1is hydrogen, C1-C6-alkyl,R2is C1-C6-alkyl,R3, R4, R5are hydrogen, C1-C6-alkyl, or R4and R5together form a bond,R6is a heterocyclic ring,n is 0, 1 or 2;which comprises preparing an intermediate of the formula VIwhere R1, R3, R4 and R5 are as defined above, followed by halogenation, thiomethylation, oxidation and acylation to give compounds of the formula I.Also novel intermediates for preparing the compounds of the formula I and novel processes for preparing the intermediates are described.

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