Liver cancer biomarkers

Details Liver cancer biomarkers Liver cancer biomarkers

2007-02-20

2011-11-29

Reddig, Peter J (Department: 1642)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

C435S007100, C435S007210, C435S007230

Reexamination Certificate

active

08067152

ABSTRACT:
A method of detecting whether a subject is afflicted with or at increased risk of developing liver cancer is carried out by detecting cleavage of a marker in a sample such as a blood sample from the subject. Suitable markers include but are not limited to, calreticulin, calreticulin precursor, protein disulfide isomerase family A member 3 (PDIA3), and cleavage products thereof. The cleavage, or extent of cleavage, can be as compared to that found in a control sample.

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