Spirohydantoin aryl CGRP receptor antagonists

Details Spirohydantoin aryl CGRP receptor antagonists Spirohydantoin aryl CGRP receptor antagonists

2006-11-14

2011-12-06

Andres, Janet L. (Department: 1622)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S018000

Reexamination Certificate

active

08071770

ABSTRACT:
Compounds of formula I:(wherein variables A1, A2, A3, A4, A5, A6, A7, B, E1, E2, E3, E4, E5, G1, G2and R6are as described herein) which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.

REFERENCES:
patent: 4722632 (1988-02-01), Campbell
patent: 5436261 (1995-07-01), Cordi et al.
patent: 7189722 (2007-03-01), Bell et al.
patent: 7192954 (2007-03-01), Bell et al.
patent: 7202251 (2007-04-01), Bell et al.
patent: 7384930 (2008-06-01), Chaturvedula et al.
patent: 7384931 (2008-06-01), Chaturvedula et al.
patent: 2006/0189600 (2006-08-01), Bell et al.
patent: 2007/0293470 (2007-12-01), Williams et al.
patent: 2008/0004304 (2008-01-01), Bell et al.
patent: 0 159 143 (1987-12-01), None
patent: WO 2004/082602 (2004-09-01), None
patent: WO 2004/082605 (2004-09-01), None
patent: WO 2006/029153 (2006-03-01), None
patent: WO 2006/031491 (2006-03-01), None
patent: WO 2006/031610 (2006-03-01), None
patent: WO 2006/031676 (2006-03-01), None
patent: WO 2006031606 (2006-03-01), None
patent: WO 2006/052378 (2006-05-01), None
patent: WO 2007/061677 (2007-05-01), None
patent: WO 2007/061692 (2007-05-01), None
patent: WO 2007/061694 (2007-05-01), None
patent: WO 2007/061695 (2007-05-01), None
patent: WO 2007/061696 (2007-05-01), None
Sarges et al., CA 108:37727, 1988.
International Preliminary Report on Patentability for PCT/US2006/044086, dated May 29, 2008.
Apr. 27, 2009 Office Action for corresponding EPO Appln. No. 06844350.6.

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