Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Reexamination Certificate
2010-03-15
2011-10-18
Marcheschi, Michael (Department: 1775)
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
C435S006120
Reexamination Certificate
active
08039250
ABSTRACT:
Apparatus, system, and methods are provided for utilizing piezoelectric material for controlling a polymer through a nanopore. A reservoir is formed filled with conductive fluid. A membrane is formed that separates the reservoir. A nanopore is formed through the membrane. The membrane comprises electrical conductive layers, piezoelectric layers, and insulating layers. The piezoelectric layers are operative to control a size of the nanopore for clamping/releasing a polymer as well as to control the thickness of part of the membrane when a voltage is applied to the piezoelectric layers. Combinations of clamping/releasing the polymer and changing the thickness of part of the membrane can move a polymer through the nanopore at any electrically controlled speed and also stretch or break a polymer in the nanopore.
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Luan Binquan
Martyna Glenn J.
Peng Hongbo
Polonsky Stanislav
Rossnagel Stephen M.
Alexanian Vazken
Cantor & Colburn LLP
Doe Shanta G
International Business Machines - Corporation
Marcheschi Michael
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