Composition and method of producing infertility in male rodents

Details Composition and method of producing infertility in male rodents Composition and method of producing infertility in male rodents

1975-08-04

1977-03-15

Ore, Dale R.

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

424 84, 424242, A01N 912

Patent

active

040125203

ABSTRACT:
Pharmaceutical preparations in dosage forms and animal feeds (baits) consisting essentially of pharmaceutically acceptable carriers, oral and injectable, compounded with a sublethal, yet effective, amount of a compound having the formula: ##STR1## and R.sub.1 and R.sub.2 are the same or different and are hydrogen, alkyl of from 1 to 17 carbon atoms, alkenyl of from 2 to 17 carbon atoms, phenyl, a heterocyclic ring such as furyl, pyrrolyl, thienyl, indolyl or pyridyl, and R.sub.1 and R.sub.2, taken together, can be a carbocyclic ring of up to 8 carbon atoms, for inducing sterility in male mammals. Methods for preventing impregnation of females by male mammals which comprises administering systemically to male mammals a sterilizing amount of a compound of the Formula l.

REFERENCES:
patent: 2065125 (1936-12-01), Dreyfus
Journal of American Chemical Society, Apr. 1952, pp. 1733 to 1736.
Chem. Abs., 1954, vol. 48, p. 13952.

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