Therapeutic compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S445000, C514S448000, C548S252000, C549S070000, C549S071000, C549S006000, C549S062000

Reexamination Certificate

active

08039496

ABSTRACT:
Disclosed herein is a compound of the formula. Therapeutic methods, compositions, and medicaments for the treatment of glaucoma or ocular hypertension related thereto are also disclosed.

REFERENCES:
patent: 6710072 (2004-03-01), Burk et al.
patent: 7091231 (2006-08-01), Donde
patent: 7507817 (2009-03-01), Old et al.
patent: 2009/0270385 (2009-10-01), Old et al.
patent: 2009/0270386 (2009-10-01), Old et al.
Horig et al. Journal of Translational Medicine, 2:44 (2004).
Schafer et al. Drug Discovery Today, 13:913 (2008).
Han et. al. (Biorganic & Medicinal Chemistry Letters 15 (2005) 3487-3490).
Orlek et al. (J. Med. Chem. 1991, 34, 2726-2735).
Anderson et al. (Eur. J. Med. Chem. 1996, 31, 417-425).
Kohara et al. (J. Med. Chem. 1996, 39, 5228-5235).
Drysdale et al. (J. Med. Chem. 1992, 35, 2573-2581).
U.S. Appl. No. 60/757,696, filed Jan. 10, 2006, David W. Old, et al.
U.S. Appl. No. 60/805,285, filed Jun. 20, 2006, David W. Old, et al.
U.S. Appl. No. 11/553,143, filed Oct. 26, 2006, Yariv Donde.

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