Snake venom inhibitor material and method of purification

Details Snake venom inhibitor material and method of purification Snake venom inhibitor material and method of purification

1975-04-10

1977-03-15

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424101, A61K 3514, A61K 3558

Patent

active

040125025

ABSTRACT:
A material extracted from snakes such as snake serum is purified to obtain an inhibitor for snake venom toxicity and/or proteolytic enzymes. Snake serum is treated to obtain a useful therapeutic agent present in the serum and attached to a high molecular weight protein molecule. The protein molecule is split and fragments thereof are removed along with unwanted antigenic protein material to thus separate a purified material having high inhibitor activity against snake venom toxicity and proteases. The resulting inhibitor material is relatively low in protein content with an increase of specific activity of many times that of crude serum.

REFERENCES:
patent: 3504083 (1970-03-01), Philpot

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