Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-11-14
2011-12-13
Saeed, Kamal (Department: 1622)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S330000, C546S194000, C546S225000
Reexamination Certificate
active
08076359
ABSTRACT:
The present invention relates to disubstituted piperidinyl renin inhibitor compounds having the structure (Formula I) and their use in treating cardiovascular events and renal insufficiency.
REFERENCES:
patent: 6051712 (2000-04-01), Binggeli et al.
patent: 1992/03429 (1992-03-01), None
patent: 2004/089903 (2004-10-01), None
patent: WO2006/094763 (2006-09-01), None
patent: WO2008/141462 (2008-11-01), None
Wayne L. Cody et al. The Discovery and Preparation of Disubstituted Novel Amino-Aryl-Piperridine-Based Renin Inhibitors; Bioorganic & Medicinal Chemistry, Elsevier Science Ltd. GB; vol. 13, No. 1, Jan. 3, 2005; pp. 59-68; *the whole document* also available on—www.sciencedirect.com.
International Search Report; Performed by—Canadian Intellectual Property Office; Date completed—Jan. 24, 2008; By Authorized Officer—Tung Siu (819) 934-6735.
Dube Daniel
Gallant Michel
Grimm Erich L.
Juteau Helene
Laliberte Sebastien
Bianchi Kristin
Cocuzzo Anna
Daniel Mark R.
McGinnis James L.
Merck Canada Inc.
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