Organic compounds and process

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2602475EP, 260268R, 26029359, 42424852, 424250, 42424858, 424267, 424269, 4242484, C07D48704

Patent

active

040124134

ABSTRACT:
Compounds of the formula: ##STR1## wherein R is hydrogen, methyl, or ethyl; wherein R' and R" are hydrogen, alkyl of 1 to 3 carbon atoms, inclusive, wherein R.sub.1 is hydrogen or methyl defined as above; wherein R.sub.2, R.sub.3, R.sub.4, and R.sub.5 are selected from the group consisting of hydrogen, alkyl defined as above, halogen, nitro, trifluoromethyl, and alkoxy and alkylthio, in which the carbon chain moieties are of 1 to 3 carbon atoms, inclusive; and wherein the 5 to 6 nitrogen-carbon linkage is selected from the group consisting of double bonds and single bonds, are produced by a variety of multistep processes.
The new compounds of formula X above and the pharmacologically acceptable acid addition salts thereof have oral and parenteral sedative and tranquilizing activity, and anti-depressant activity and can be employed for tranquilizing mammals as well as combating anxiety and depressions.

REFERENCES:
patent: 3391138 (1968-07-01), Archer et al.
patent: 3767661 (1973-10-01), Hester
Allgeier et al., Chem. Abstracts, vol. 77, Abstract No. 126711r, (1972).

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