Chemical composition of hydrogels for use as articulating...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

Reexamination Certificate

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C525S050000, C526S319000

Reexamination Certificate

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08034362

ABSTRACT:
The present invention provides a hydrogel composition comprising at least one polymer with functional groups including alcohol groups, acid groups, and amide groups and where the ratio of the functional alcohol groups to functional acid groups in the hydrogel composition ranges from about 16:1 to about 3:2. The present invention also provides a method of repairing an articulating surface in a body using the inventive composition. The inventive hydrogel composition is created by blending two or more polymers to achieve the desired ratio of functional groups, reacting at least one polymer with a reagent that results in the formation of alcohol, acid, and/or amide functional groups of the desired ratio, and/or polymerizing at least one monomer to achieve the desired ratio of functional groups.

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