Method of two-dimensionally arraying ferritin on substrate

Combinatorial chemistry technology: method – library – apparatus – Method of creating a library – Solid-phase synthesis or particular method of cleavage from...

Reexamination Certificate

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C506S030000, C530S300000, C530S324000, C530S327000, C530S350000

Reexamination Certificate

active

07825070

ABSTRACT:
A novel method for two-dimensionally arraying ferritin on a substrate is provided which obviates the need for a metal ion that permits linking between adjacent two ferritin particles. In a method of two-dimensionally arraying ferritin on a substrate, the surface of the substrate is hydrophilic, and the method includes the steps of: developing a solution containing a solvent and the ferritin on the substrate; and removing the solvent from the solution developed on the substrate, while the ferritin has an amino acid sequence set out in SEQ ID NO: 1 modified at its N-terminus.

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Matsui et al “Realizing a Two-Dimensional Ordered Array of Ferritin Molecules Directly on a Solid Surface Utilizing Carbonaceous Material Affinity Peptides” pp. 1615-1618 Langmuir 2007 vol. 23 The American Chemical Society , Published on the web Jan. 11, 2007.
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