Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2004-11-22
2010-11-09
Landsman, Robert (Department: 1647)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C424S094640, C435S068100, C530S308000
Reexamination Certificate
active
07829307
ABSTRACT:
GLP-2 peptides and analogs thereof are produced in high yield and with desired, authentic termini by isolation from a GLP-2 peptide multimer in which at least two units of GLP-2 peptide are coupled through a linker that presents an N-terminal acid cleavage site and a C-terminal enzyme cleavage site. In a specific embodiment, [Gly2]hGLP-2 is produced from a multimeric precursor comprising 2-30 units thereof.
REFERENCES:
patent: 4336336 (1982-06-01), Silhavy et al.
patent: 4551433 (1985-11-01), DeBoer
patent: 4588684 (1986-05-01), Brake
patent: 4689406 (1987-08-01), Banks et al.
patent: 4738921 (1988-04-01), Belagaje et al.
patent: 4745056 (1988-05-01), Guterman et al.
patent: 4837148 (1989-06-01), Cregg
patent: 4870023 (1989-09-01), Fraser et al.
patent: 4873192 (1989-10-01), Kunkel
patent: 4876197 (1989-10-01), Burke et al.
patent: 4880734 (1989-11-01), Burke et al.
patent: 4929555 (1990-05-01), Cregg et al.
patent: 5110729 (1992-05-01), Maeda et al.
patent: 5352771 (1994-10-01), Kostic et al.
patent: 5393924 (1995-02-01), Tafesh et al.
patent: 5416007 (1995-05-01), Charette et al.
patent: 5420242 (1995-05-01), Gautvik et al.
patent: 5457066 (1995-10-01), Frank et al.
patent: 5580751 (1996-12-01), Buchardt et al.
patent: 5595887 (1997-01-01), Coolidge et al.
patent: 5602034 (1997-02-01), Tekamp-Olson
patent: 5629205 (1997-05-01), Lagosky
patent: 5707826 (1998-01-01), Wagner et al.
patent: 5728543 (1998-03-01), Dorschug et al.
patent: 5789379 (1998-08-01), Drucker et al.
patent: 5814603 (1998-09-01), Oldenburg et al.
patent: 5851810 (1998-12-01), Blanchard
patent: 5853976 (1998-12-01), Hesse et al.
patent: 5912229 (1999-06-01), Thim et al.
patent: 6130063 (2000-10-01), Lawlis
patent: 6171823 (2001-01-01), Woldike et al.
patent: 6184201 (2001-02-01), Drucker et al.
patent: 6313092 (2001-11-01), Holladay et al.
patent: 6316224 (2001-11-01), Xia
patent: 6461834 (2002-10-01), Dormady et al.
patent: 6660758 (2003-12-01), Nicolaou et al.
patent: 6660763 (2003-12-01), Tang et al.
patent: 6703484 (2004-03-01), Chatterjee et al.
patent: 7335486 (2008-02-01), Wagner et al.
patent: 2005/0221444 (2005-10-01), Williams et al.
patent: 2005/0227313 (2005-10-01), Seo et al.
patent: 2005/0260701 (2005-11-01), Wagner et al.
patent: 2005/0287632 (2005-12-01), Holmquist et al.
patent: 2006/0008870 (2006-01-01), Wagner et al.
patent: 2006/0024778 (2006-02-01), Wagner et al.
patent: 0164556 (1958-12-01), None
patent: 0036259 (1981-09-01), None
patent: 0036776 (1981-09-01), None
patent: 0060057 (1982-09-01), None
patent: 0063953 (1982-11-01), None
patent: 0121775 (1984-10-01), None
patent: 0127839 (1984-12-01), None
patent: 0136829 (1985-04-01), None
patent: 0136907 (1985-04-01), None
patent: 0155476 (1985-09-01), None
patent: 0267851 (1988-05-01), None
patent: 0284044 (1988-09-01), None
patent: 0329203 (1989-08-01), None
patent: 0473128 (1992-03-01), None
patent: 0978565 (2000-02-01), None
patent: WO 9317110 (1993-09-01), None
patent: WO 95/17510 (1995-06-01), None
patent: WO 9517510 (1995-06-01), None
patent: WO 9617941 (1996-06-01), None
patent: WO 9803664 (1998-01-01), None
patent: WO 9964611 (1999-12-01), None
patent: WO 0006763 (2000-02-01), None
patent: WO 0026418 (2000-05-01), None
patent: WO 0028067 (2000-05-01), None
patent: WO 01/49314 (2001-07-01), None
patent: WO 02061105 (2002-08-01), None
patent: WO 03099848 (2003-12-01), None
patent: WO 03099854 (2003-12-01), None
patent: WO 03100022 (2003-12-01), None
patent: WO 2004011599 (2004-02-01), None
Chang, J. (1985)Eur. J. Biochem. 151, 217-224.
Buhl et al.,J. Biol. Chem., 1988, 263(18):8621.
Advisory Action issued in U.S. Appl. No. 10/997,697 dated Oct. 1, 2008.
Advisory Action issued in U.S. Appl. No. 10/997,762 dated Jul. 15, 2008.
Aubin, et al. “Highly effective delivery of foreign DNA to adherent cells via polybrene/DMSO-assisted gene transfer”, Methods Mol. Biol., 62 (1997), 319-42.
Beach, et al. “Functionally homologous cell cycle control genes in budding and fission yeast”, Nature, 300(5894), Dec. 23, 1982, 706-9.
Birnstiel, et al., “Transcription termination and 3′ procession: the end is in site!”, Cell, 41(2), Jun. 1985, 349-59.
Catsimpoolas, et al., “Specific cleavage of cystine peptides by cyanide”, J. of Biol. Chem., 241(8), Apr. 25, 1996, 1790-6.
Coombs, et al. “Substrate specificity of prostate-specific antigen (PSA)”, Chem Biol. 5(9), Sep. 1998, 475-88.
Dargatz, et al., “The heterodimeric protease clostripain fromClostridium histolyticumis encoded by a single gene”, Molecular and General Genetics, vol. 240, No. 1, Jul. 1, 1993, 140-145.
Davies, et al., “Plasmid-determined resistance to antimicrobial agents”, Anu. Rev. Microbiol. 32, 1978, 469-508.
Database EMBL (online), Jul. 12, 2001, “Glucagon [homo sapiens]”, XP002501257 retrieved from NCBI on Apr. 21, 2009, database accession No. AAH05278, the whole document.
Dijkema, et al., “Cloning and expression of the chromosomal immune interferon gene of the rat”, EMBO J. 4(3), Mar. 1985, 761-7.
Djuran, et al., “Hydrolysis of amide bond in histidine-containing peptides promoted by chelated amino acid palladium(II) complexes: dependence of hydrolytic pathway on the coordination modes of the peptides”, Polyhedron 18(27), Sep. 14, 1999, 3611-3616.
Dou, et al., “Preliminary study on the cleavage of fusion protein GST-CMIV with palladate(II) complex”, Preparative Biochem. & Biotechnol. 2000, vol. 30, No. 1, 69-78.
Drexler, et al., “Palladium(II) and platinum(II) complexes with 1,5-dithiacycolooctane(dtco): structures of Pd(dtco)C12and Pd(dtco2)(NO3)2and kinetics of ligand substitution in [Pd(dtco2)]2+by bidenate ligands”, Inorganic Chemistry, 30, 1991, 1297-1302.
Dykes, et al., “Expression of atrial natriuretic factor as a cleavable fusion protein with chloramphenicol acetyltransferase inEscherichia coli”, Eur. J. Biochem., 174(2), Jun. 1, 1988, 411-6.
Felgner, et al., “Enhanced gene delivery and mechanism studies with a novel series of cationic lipid formulations”, J. Biol. Chem. 269(4), Jan. 28, 1994, 2550-61.
Forsberg, et al., “An evaluation of different enzymatic cleavage methods for recombinant fusion proteins, applied on des(1-3)insulin-like growth factor I”, J. Protein Chem., 11(2), Apr. 1992, 201-11.
Forsberg, et al., “Comparison of two chemical cleavage methods for preparation of a truncated form of recombinant human insulin-like growth factor I from a secreted fusion protein”, Biofactors, 2(2), Dec. 1989, 105-12.
Gluzman, “SV40-Transformed simian cells support the replication of early sv40 mutants”, Cell, 23(1), Jan. 1981, 175-182.
Gram, et al., “A novel approach for high level production of a recombinant human parathyroid hormone fragment inEscherichia coli”, Bio/Technology, 12(10), Oct. 1994, 1017-23.
Greger, et al., “Poly(A) signals control both transcriptional termination and initiation between the tandem GAL10 and GAL7 genes ofSaccharomyces cerevisiae”, EMBO J. 17(16), Aug. 17, 1998, 4771-9.
Guo, et al., “Protein tolerance to random amino acid change”, 2004, Proc. Natl. Acad. Sci. 101: 9205-9210.
Hill, “Functional analysis of conserved histidines in ADP-Glucose pyrophophorylase fromEscherichia coli”, 1998, Biochem. Biophys. Res. Comm. 244:573-577.
Hohmann, et al., “Rate and equilibrium data for substitution reactions of diaqua(ethylenediamine)palladium(II) with chloride in aqueous solution”, Inorg Chim Acta, 174(1), 1990, 87-92.
International Preliminary Examination Report issued in International Application No. PCT/US2003/16645 mailed Nov. 12, 2004.
International Search Report issued in International Application No. PCT/US2003/16645 mailed May 24, 2004.
International Preliminary Examination Report issued in International Application No. PCT/US2003/16469 mailed Feb. 9, 2005.
International Search Report issued in International Application No. PCT/US2003/16469
Araujo Alberto de
Sasaki Ken
Walczyk Ewa
Williamson Vanessa Jane
Dang Ian
Landsman Robert
NPS Pharmaceuticals Inc.
Stoel Rives LLP
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