Polynucleotides encoding a truncated ORF2 from Corynebacterium

Details Polynucleotides encoding a truncated ORF2 from Corynebacterium Polynucleotides encoding a truncated ORF2 from Corynebacterium

2004-02-04

2010-06-22

Steadman, David J (Department: 1656)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023200, C435S115000, C435S194000

Reexamination Certificate

active

07741460

ABSTRACT:
The invention provides methods to increase the production of an amino acid fromCorynebacteriumspecies by way of the amplification of amino acid biosynthetic pathway genes in a host cell chromosome. Amplification may be by integration of one or more copies of a gene or genes into a host cell chromosome. One gene that may be incorporated is the gene ORF2, which encodes an unnamed hypothetical protein and which may be obtained fromCorynebacterium glutamicum. The invention also provides novel isolated nucleic acid molecules for L-lysine biosynthetic pathway genes ofCorynebacterium glutamicum.

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