Methods and kits for volumetric distribution of...

Details Methods and kits for volumetric distribution of... Methods and kits for volumetric distribution of...

2003-10-21

2010-06-29

Sirmons, Kevin C (Department: 3767)

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

C604S529000, C600S433000

Reexamination Certificate

active

07744584

ABSTRACT:
Methods and kits for delivering pharmaceutical agents to the adventitia and other regions outside the external elastic lamina (EEL) surrounding a blood vessel utilize a catheter having a needle. The needle is positioned in up to 5 mm beyond the EEL and delivers an amount of pharmaceutical agent sufficient to circumferentially permeate around the blood vessel and, in many cases, extend longitudinally and radially along the blood vessel. Confirmation that a delivery aperture of the needle lies beyond the EEL may be required before delivering the pharmaceutical agent.

REFERENCES:
patent: 5112305 (1992-05-01), Barath et al.
patent: 5196024 (1993-03-01), Barath
patent: 5354279 (1994-10-01), Hofling
patent: 5538504 (1996-07-01), Linden et al.
patent: 5645564 (1997-07-01), Northrup et al.
patent: 5681281 (1997-10-01), Vigil et al.
patent: 5693029 (1997-12-01), Leonhardt
patent: 5722989 (1998-03-01), Fitch et al.
patent: 6059815 (2000-05-01), Lee et al.
patent: 6102933 (2000-08-01), Lee et al.
patent: 6283947 (2001-09-01), Mirzaee
patent: 6547803 (2003-04-01), Seward et al.
patent: 2003/0040712 (2003-02-01), Ray et al.
patent: 2003/0078562 (2003-04-01), Makower et al.
patent: 2003/0120297 (2003-06-01), Beyerlein
patent: 2003/0171734 (2003-09-01), Seward et al.
patent: 2004/0067197 (2004-04-01), Leclerc et al.
patent: 2005/0090714 (2005-04-01), Greff
patent: 2006/0189941 (2006-08-01), Seward et al.
Altman et al., Exploring heart lymphatics in local drug delivery, Lymph. Res. Biol., (2003) 1:47-54.
Daschner et al., Penetration of gentamicin into heart valves, subcutaneous and muscular tissue of patients undergoing open heart surgery, J. Cardiovasc. Surg., (1986) 581-584.
Laham et al., Intracoronary and intravenous administration of basic fibroblast growth factor: myocardial and tissue distribution, Drug Met. Disp., (1999) 27:821-826.
Laham et al., Intrapericardial administration of basic fibroblast growth factor: myocardial and tissue distribution and comparison with intracoronary and intravenous administration, Cath Cardio. Interv., (2003) 58:375-381.

Affiliated with

Also associated with

Rating

Methods and kits for volumetric distribution of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods and kits for volumetric distribution of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and kits for volumetric distribution of... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4246488