Antimicrobial and radioprotective compounds

Details Antimicrobial and radioprotective compounds Antimicrobial and radioprotective compounds

2007-10-24

2010-11-02

Chu, Yong (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S464000, C514S466000, C514S434000, C514S394000, C548S304400, C548S217000, C549S434000

Reexamination Certificate

active

07825145

ABSTRACT:
The present invention relates to a method of treatment and/or prophylaxis of a microbial infection, comprising the step of administering an effective amount of a compound of formula (I), in which X and Y are either the same or different and selected from a heteroatom; is a double or single bond depending on the heteroatoms X and Y; R1to R5are either the same or different and selected from hydrogen or a non-deleterious substituent; and R6and R7are either the same or different and selected from hydrogen and a non-deleterious substituent or one of R6and R7are absent when there is a double bond present, pharmaceutically acceptable salts or derivatives, pro-drugs, tautomers and/or isomers thereof. The present invention also relates to a method for protecting a subject from radiation damage, a method of cancer radiotherapy and use as an antimicrobial or radioprotective agent of the compound of formula (I) defined above. Some of the compounds of formula (I) are novel and are also described in the present invention, together with pharmaceutical or veterinary compositions containing them.

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