Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2007-05-09
2010-06-15
Martinell, James (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S007100, C435S243000
Reexamination Certificate
active
07736855
ABSTRACT:
Disclosed in this specification is a process for separating a microorganism from a sample by selectively hybridizing the microorganism's nucleic acid with a labeled probe. Suitable labels include antigens as well an enzymes. In one embodiment, an antigen is introduced to the sample which is activated by the enzyme. The labeled microorganism is then exposed to a substrate that is coated with an antibody which is specific to the activated antigen, thus binding the labeled microorganism to the substrate. The substrate may be, for example, a magnetic substrate such as a paramagnetic bead.
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Orphan Victoria J.
Pernthaler Annelie
California Institute of Technology
Martinell James
Milstein Joseph B.
Milstein Zhang & Wu LLC
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