Isolated cold-and-menthol-sensitive receptor (CMR1)

Details Isolated cold-and-menthol-sensitive receptor (CMR1) Isolated cold-and-menthol-sensitive receptor (CMR1)

2008-02-15

2010-11-16

Landsman, Robert (Department: 1647)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Reexamination Certificate

active

07834150

ABSTRACT:
The present invention relates to regulation of cold sensation and pain. More particularly, the present invention is directed to nucleic acids encoding a member of the transient regulatory protein family, CMR1, which is involved in modulation of the perception of cold sensations and pain. The invention further relates to methods for identifying and using agents that modulate cold responses and pain responses stimulated by cold via modulation of CMR1 and CMR1-related signal transduction.

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