Macrolides having immunosuppressive activity

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514411, 514183, 540456, C07D49116, A61K 31345

Patent

active

058771840

ABSTRACT:
Macrolides of the general structural Formula I: ##STR1## are immunosuppressants useful in a mammalian host for the treatment of autoimmune diseases, infectious diseases and/or the prevention of rejection of foreign organ transplants and/or related afflictions, diseases and illnesses.

REFERENCES:
patent: 5189042 (1993-02-01), Goulet et al.
patent: 5344925 (1994-09-01), Goulet et al.
patent: 5349061 (1994-09-01), Sinclair et al.
patent: 5561137 (1996-10-01), Or et al.
patent: 5563172 (1996-10-01), Wagner et al.

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