Method of determining inhibition of binding to TRPM7 protein

Details Method of determining inhibition of binding to TRPM7 protein Method of determining inhibition of binding to TRPM7 protein

2004-12-22

2010-12-28

Chernyshev, Olga N (Department: 1649)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S007210, C436S501000

Reexamination Certificate

active

07858322

ABSTRACT:
This invention relates to methods of reducing the damaging effect of an injury to mammalian cells by treatment with compounds which reduce cell death or dysfunction, including cellular damage following episodes of tissue ischemia, trauma, epilepsy, and acute or chronic degeneration. The invention discloses methods of treating these disorders by administering inhibitors that disrupt protein-protein interactions involved in these disorders, screening methods to identify such inhibitors and specific compositions useful for treating these disorders.

REFERENCES:
patent: 2450236 (2003-01-01), None
patent: 2457424 (2003-02-01), None
patent: 2004/45535 (2004-06-01), None
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PCT International Search Report mailed Apr. 20, 2005, PCT Application No. PCT/CA2004/002193, filed Dec. 22, 2004.

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