Regulation of kinase, regulated in COPD kinase (RC kinase)

Details Regulation of kinase, regulated in COPD kinase (RC kinase) Regulation of kinase, regulated in COPD kinase (RC kinase)

2004-06-16

2010-11-09

Ton, Thaian N (Department: 1632)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023100, C536S023500, C435S325000, C424S093200, C424S093210

Reexamination Certificate

active

07829685

ABSTRACT:
Reagents which regulate human RC Kinase activity and reagents which bind to human RC Kinase gene products can be used to regulate this protein for therapeutic effects. Such regulation is particularly useful for treating chronic obstructive pulmonary disease, asthma, cancer, and diseases in which cell signaling is defective.

REFERENCES:
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patent: WO02/33099 (2002-04-01), None
patent: WO 02090525 (2002-11-01), None
patent: WO03/018786 (2003-03-01), None
patent: PCT/EP2004/006474 (2004-11-01), None
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Alignment of SEQ ID No. 4 and 10 to WO 02/090525.
Seffernick et al. J. Bacteriol. 183(8):2405-2410, 2001.
GenBank Accession No. AK122935.
GenBank Accession No. AC016725.
Puchelle et al., 2001 “Chronic Obstructive Pulmonary Disease: An old Disease with Novel Concepts and Drug Strategies,”Trends in Pharmacological Sciences, 22(10): 495-497.
Rahman Irfan, 2002 “Oxidative Stress and Gene Transcription in Asthma and Chronic Obstructive Pulmonary Disease: Antioxidant Therapeutic Targets,”Current Drug Targets—Inflammation and Allergy, 1(3): 291-315.

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