Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2007-08-24
2010-02-02
Chen, Stacy B (Department: 1648)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C424S228100
Reexamination Certificate
active
07655419
ABSTRACT:
The invention features methods and compositions for screening for agents that modulate replication of a virus, particularly Flaviviridae virus (particularly hepatitis C virus (HCV)), where the methods provide for detection of agents that modulate the binding of TBC and NS5A, the inhibition of TBC activity, inhibition of Rab1 activity, and/or the expression of the TBC protein and/or Rab1 protein. The invention also features methods of controlling viral replication, and agents useful in such methods.
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Glenn Jeffrey
Oakes Tina Myers
Sklan Ella
Staschke Kirk A.
Bozicevic Field & Francis LLP
Chen Stacy B
Eli Lily and Company
Francis Carol L.
The Board of Trustees of the Leland Stanford Junior University
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