Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Reexamination Certificate
2005-11-01
2010-12-07
Sullivan, Daniel M (Department: 1621)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
C514S561000, C424S439000, C554S035000
Reexamination Certificate
active
07846972
ABSTRACT:
The present invention relates to multimeric oleamide derivatives having connexin 26 inhibitory activities and embraces the dimer oleamide derivatives represented by the following formula (1) or a pharmacologically acceptable salt thereof:where n denotes an integer of 3, 5, or 8. The novel oleamide derivatives of the present invention can be used not only as research reagents, but also in a wide industrial field because they exhibit useful bioactivities such as cancer metastasis/growth inhibition. Thus they have various applications, such as in medicines, supplements, and functional foods, in addition to cancer-preventive and cancer-therapeutic drugs.
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Kita Yasuyuki
Nojima Hiroshi
Cutliff Yate K
Osaka University
Roylance Abrams Berdo & Goodman LLP
Sullivan Daniel M
The New Industrial Research Organization
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