Process for the production of β-amino acids using acylase

Details Process for the production of β-amino acids using acylase Process for the production of β-amino acids using acylase

2007-10-26

2010-11-16

Ramirez, Delia M (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

C435S252100, C435S252300

Reexamination Certificate

active

07833760

ABSTRACT:
The present invention relates to aVariovoraxsp. which produces an acylase having an asymmetric hydrolysis activity on an N-acetyl β-amino acid to selectively produce an R-β-amino acid, and aBurkholderiasp. which produces both an acylase having an asymmetric hydrolysis activity on an N-acetyl β-amino acid to selectively produce an S-β-amino acid and an acylase having an asymmetric hydrolysis activity of an N-acetyl β-amino acid to selectively produce an R-β-amino acid, and a process for the selective production of an S-, or R-β-amino acid using the above strains.

REFERENCES:
patent: 6214609 (2001-04-01), Landis et al.
patent: 6893852 (2005-05-01), Izui et al.
patent: 6905819 (2005-06-01), Matsuzaki et al.
patent: 7244569 (2007-07-01), Matsuzaki et al.
patent: 2003/0054506 (2003-03-01), Otsuna et al.
patent: 2005/0214912 (2005-09-01), Nozaki et al.
patent: 2006/0263861 (2006-11-01), Nozaki et al.
patent: 2007/0026504 (2007-02-01), Suzuki et al.
patent: WO98/50575 (1998-11-01), None
patent: WO03/020943 (2003-03-01), None
patent: WO03/080854 (2003-10-01), None
Gröger, H., et al., “The first aminoacylase-catalyzed enantioselective synthesis of aromatic β-amino acids,” Org. Biomol. Chem. 2004;2(14):1977-1978.
Lin, P-H., et al., “Identification and characterization of a new fene fromVariovorax paradoxusIso1 encodingN-acyl-D-amino acid amidohydrolase responsible for D-amino acid production,” Eur. J. Biochem. 2002;269:4868-4878.
Soloshonok, V.A., et al., “Biocatalytic Approach to Enantiomerically Pure β-Amino Acids,” Tetrahedron:Asymmetry 1995;6(7):1601-1610.
European Search Report for EP Appl. No. 05016796.4 (Nov. 7, 2005).
U.S. Appl. No. 11/782,260, filed Jul. 24, 2007, Suzuki et al.

Affiliated with

Also associated with

Rating

Process for the production of β-amino acids using acylase does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the production of β-amino acids using acylase, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the production of β-amino acids using acylase will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4220458