Water-soluble zinc ionophores, zinc chelators, and/or zinc...

Details Water-soluble zinc ionophores, zinc chelators, and/or zinc... Water-soluble zinc ionophores, zinc chelators, and/or zinc...

2009-03-24

2010-11-23

Aulakh, Charanjit S (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S261000

Reexamination Certificate

active

07838536

ABSTRACT:
Disclosed herein are novel zinc ionophores, zinc chelators and/or zinc complexes with enhanced aqueous solubility. Methods of treating cancer using at least one zinc ionophore and/or zinc chelator are also disclosed. Also disclosed herein are compositions and methods for treating cancer with combination therapy using at least one texaphyrin metal complex and at least one zinc ionophore or the respective pharmaceutically acceptable derivatives or salts thereof.

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