Nucleic acids encoding B7-H4, a T cell immunoregulatory...

Details Nucleic acids encoding B7-H4, a T cell immunoregulatory... Nucleic acids encoding B7-H4, a T cell immunoregulatory...

2007-10-30

2010-12-07

Ouspenski, Ilia (Department: 1644)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S320100, C435S252300, C435S069100

Reexamination Certificate

active

07847081

ABSTRACT:
The invention provides novel B7-H3 and B7-H4 polypeptides useful for co-stimulating T cells, isolated nucleic acid molecules encoding them, vectors containing the nucleic acid molecules, and cells containing the vectors. Also included are methods of making and using these co-stimulatory polypeptides.

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Skolnick et al., Trends in biotech., 18(1):34-39, 2000.
Coyle et al., Nature Immunol., 2:203-209, 2001.
Metzler et al., Nature Structural Biol., 4:527-531, 1997.

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