Screening and crystallization plates for manual and...

Single-crystal – oriented-crystal – and epitaxy growth processes; – Processes of growth from liquid or supercritical state – Having growth from a solution comprising a solvent which is...

Reexamination Certificate

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C117S069000, C422S245100

Reexamination Certificate

active

07666259

ABSTRACT:
In one embodiment, a crystallization and screening plate comprises a plurality of cells open at a top and a bottom, a frame that defines the cells in the plate, and at least two films. The first film seals a top of the plate and the second film seals a bottom of the plate. At least one of the films is patterned to strongly pin the contact lines of drops dispensed onto it, fixing their position and shape. The present invention also includes methods and other devices for manual and high-throughput protein crystal growth.

REFERENCES:
patent: 5096676 (1992-03-01), McPherson et al.
patent: 7470324 (2008-12-01), Hoffmann
patent: 2003/0159641 (2003-08-01), Sanjoh et al.
patent: 2004/0187958 (2004-09-01), Viola et al.
Quere, D. and Bico, J. “Controlled Wetting by Surface Patterning.” Houille Blanche-Revue Int. De L Eau. 2003. pp. 21-24.
McPherson, A. “Crystallization of Biological Macromolecules.” (1999). pp. 176-196.
Daoura, M. J. and Meldrum, D. R. “Precise Automated Control of Fluid Volumes Inside Glass Capillaries” IEEE Journal of Microelectromechanical Systems, vol. 8, No. 1, Mar. 1999. pp. 71-77.
Meldrum, D. R. et al. “ACAPELLA-1K, A Capillary-Based Submicroliter Automated Fluid Handling System for Genome Analysis” Genome Res. 10(1): (2000). pp. 95-104.
Zheng, B. et al. “Screening of Protein Crystallization Conditions on a Microfluidic Chip Using Nanoliter-Size Droplets.” (2003). J. Am. Chem. Soc. 9 vol. 125, No. 37, 2003. pp. 11170-11171.
Zheng, B. et al. “Formation of Arrayed Droplets by Soft Lithography and Two-Phase Fluid Flow, and Application in Protein Crystallization.” Adv. Mater. 16(15), 2004. pp. 1365-1368.
Zheng, B. et al. “A Droplet-Based, Composite PDMS/Glass Capillary Microfluidic System for Evaluating Protein Crystallization Conditions by Microbatch and Vapor-Diffusion Methods with On-Chip X-Ray Diffraction” Angew. Chem. Int. Edit. 43(19). 2004 pp. 2508-2511.
Kalinin, Y. and Thorne, R. E. “Crystal growth in X-ray-transparent plastic tubing an alternative for high-throughput applications” Acta Cryst. D61, 2005, pp. 1528-1532.
Berejnov, V. and Thorne, R.E. “Enhancing drop stability in protein crystallization by chemical patterning.” Acta Cryst. D61, 2005, pp. 1563-1567.
Kalinin, Y. et al. , “A new sample mounting technique for room-temperature macromolecular crystallography” J. Appl. Cryst. 38, 2005, pp. 333-339.
Abbott, N. L. et al. “Manipulation of the Wettability of Surfaces on the 0.1 to 1-Micrometer Scale Through Micromachining and Molecular Self-Assembly.” Science 257, 1992. pp. 1380-1382.
Xia, Y. et al. “Surface patterning and its application in wetting/dewetting studies” (2001). Current Op. in Colloid & Interface Sci. 6, 2001. pp. 54-64.
Andersen, J. V. et al. “Pinning of a solid-liquid-vapor interface by stripes of obstacles.” Phys. Rev. E vol. 53. No. 5. 1996, pp. 5006-5010.
Buehrle, J. et al. “Impact of Line Tension on the Equilibrium Shape of Liquid Droplets on Patterned Substrates.” Langmuir, vol. 18, No. 25, 2002, pp. 9771-9777.
Yoshimitsu, Z., et al. “Effects of Surface Structure on the Hydrophobicity and Sliding Behavior of Water Droplets” Langmuir, vol. 18, No. 15, 2002. pp. 5818-5822.
Callies, M. et al. “Microfabricated textured surfaces for super-hydrophobicity investigations” Microelectronic Engineering 78-79, 2005. pp. 100-105.
Crysel, W. B. et al. “The international space station X-ray crystallography facility.” Journal of Crystal Growth. 232. 2001. pp. 458-467.
B. Zheng, et al. “Using nanoliter plugs in microfluidics to facilitate and understand protein crystallization.” Current Opinion in Structural Biology, 15, 2005, pp. 548-555.
Neuro Probe, Inc., Protein Crystallography. 2006. http://www.neuroprobe.com/products/crystallography.html.
Greiner Bio One, Protein Crystallization catalog. http://www.greinerbioone.com/en/usa/articles/catalogue/articles/605—10.
Corning, Inc. Corning Life Sciences Catalog. http://catalog2.corning.com/Lifesciences/en-US/Search/search.aspx?searchfor=protein+crystallization&selprodids=.
Hampton Research, Crystallization Plates & Accessories. 2003. http://www.hamptonresearch.com/products/Subcategory.aspx?cid=10.
Art Robbins Instruments, Crystallography Products. 2004. http://web.archive.org/web/20070607180623/www.artrobbinsinstruments.com/crystallography.html.
Fluidigm, Corporation, The TOPAZ® System—Protein Crystallization by Fluidigm. http://www.fluidigm.com/topaz.htm.
Protein Crystallography Times, vol. 1, No. 2, Mar. 2009 www.rigaku.com/downloads
ewsletter/LifeSciencesV01N02.html.
http://www.nexusbio.com/Images/products—images/ProteinCrystal—images/pc—well.jpg.
Kalinin et al. “Controlling microdrop shape and position for biotechnology using micropatterned rings”, Microfluidics and Nanofluidics 5: 449-454 (2008).
Kalinin et al “Contact line pinning by microfabricated patterns: Effect of microscale topography”, Langmuir 25 (9), 5391-5397 (2009).
Soliman et al. “X-ray Transparent Crystallization Plates for High Performance Crystallization” presented in Apr. 2009 at a Protein Structure Initiative Meeting at the NIH in Bethesda, MD.

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