Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Patent
1990-11-19
1992-05-26
Cintins, Marianne
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
544142, 544143, 546200, 546201, 548452, 548454, 548455, C07D41300
Patent
active
051169789
ABSTRACT:
A process for producing a bis-(indolyl)ethylene of the formula ##STR1## is described, wherein A, B, a, b, R, Z, R.sup.5', R.sup.6 and R.sup.6' are as defined in the specification, said method comprising reacting an indole of the formula ##STR2## with an acylindole of the formula in the presence of a Vilsmeier reagent selected from the group consisting of phosphoryl chloride, phosgene, oxalyl chloride, benzoyl chloride, thionyl chloride, alkanesulfonyl chloride, arene-sulfonyl chloride, alkylchoroformate, and arylchloroformate, together with a Lewis Acid selected from the group consisting of zinc chloride, boron trifluoride and aluminum chloride.
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Appleton Papers Inc.
Cintins Marianne
Mieliulis Benjamin
Nguyen Jessica H.
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