Peptides with the capacity to bind to transforming growth...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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Details

C514S015800, C530S326000, C530S327000, C530S328000

Reexamination Certificate

active

07666841

ABSTRACT:
The described peptides possess the capacity to bind to Transforming Growth Factor TGF-β1 (TGF-β1), and are potential inhibitors of the biological activity of TGF-β1 through direct binding to this cytokine. These peptides can be used in the treatment of diseases or pathological alterations based on excessive or deregulated TGF-β1 expression.

REFERENCES:
patent: 2146552 (2000-08-01), None
patent: 8151396 (1996-06-01), None
patent: 0024782 (2000-05-01), None
Ishikawa, S. et al., “GD1α-replica peptides functionally mimic GD1α, an adhesion molecule of metastatic tumor cells, and suppress the tumor metastasis,” FEBS Letters, 1998, vol. 441, pp. 20-24.
Dotor De Las Herrerias et al., “International Search Report,” Oct. 8, 2004.

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